Clinical evaluation reveals tumor recurrence in peripheral nerve sheath tumor patients linked to older age and biomarker loss, highlighting criteria for postsurgical monitoring.
Key Points
Recurrence of peripheral nerve sheath tumors occurs mostly within one year of surgery, driven by larger initial tumor size, older age, and distinct immunohistochemical profiles.
Tumor relapse risk was 8.79 times higher for malignant peripheral nerve sheath tumors over 11.5 cm and 2.9 times higher in patients aged 49 years or older.
Evaluation of 122 surgical patients using electroneuromyography, magnetic resonance imaging, and Ki67 with SOX10 markers supports enhanced risk stratification protocols.