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June 8, 2024New England Journal of Medicine916 citations

Tirzepatide for Metabolic Dysfunction–Associated Steatohepatitis with Liver Fibrosis

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RLRohit LoombaMHMark L. HartmanELEric Lawitz

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Abstract

Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease associated with liver-related complications and death. The efficacy and safety of tirzepatide, an agonist of the glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, in patients with MASH and moderate or severe fibrosis is unclear.

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Loomba et al. (2024) studied this question.

synapsesocial.com/papers/68e65879b6db6435875e7d1fhttps://doi.org/10.1056/nejmoa2401943
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