Mp44-04 Rapn in Patients With Chronic Kidney Disease—a Multicentric Analysis

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy III (MP44)1 May 2024MP44-04 RAPN IN PATIENTS WITH CHRONIC KIDNEY DISEASE—A MULTICENTRIC ANALYSIS Olga Katzendorn, Christian Fuhrmann, Frank Schiefelbein, Georg Schoen, Clemens Wiesinger, Jacob Pfuner, Burkhard Ubrig, Simon Gloger, Philipp Nuhn, Ahmed Eraky, Christian Wagner, Abdirahman Ayanle, Claudia Kesch, Mulham Al-Nader, Boris A. Hadaschik, Pouriya Faraj Tabrizi, Markus A. Kuczyk, Stefan Siemer, Michael Stöckle, Philip Zeuschner, and Nina N. Harke Olga KatzendornOlga Katzendorn , Christian FuhrmannChristian Fuhrmann , Frank SchiefelbeinFrank Schiefelbein , Georg SchoenGeorg Schoen , Clemens WiesingerClemens Wiesinger , Jacob PfunerJacob Pfuner , Burkhard UbrigBurkhard Ubrig , Simon GlogerSimon Gloger , Philipp NuhnPhilipp Nuhn , Ahmed ErakyAhmed Eraky , Christian WagnerChristian Wagner , Abdirahman AyanleAbdirahman Ayanle , Claudia KeschClaudia Kesch , Mulham Al-NaderMulham Al-Nader , Boris A. HadaschikBoris A. Hadaschik , Pouriya Faraj TabriziPouriya Faraj Tabrizi , Markus A. KuczykMarkus A. Kuczyk , Stefan SiemerStefan Siemer , Michael StöckleMichael Stöckle , Philip ZeuschnerPhilip Zeuschner , and Nina N. HarkeNina N. Harke View All Author Informationhttps://doi.org/10.1097/01.JU.0001009508.69111.d0.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patients with chronic kidney disease (CKD) are a vulnerable patient cohort in which good functional und oncologic outcomes are crucial. In this study, we investigated perioperative results of robot-assisted partial nephrectomy (RAPN) in patients with CKD. METHODS: A multicentric dataset of 2059 RAPN was retrospectively analyzed. CKD stage was defined according to KDIGO 2012 criteria and patients were dichotomized in moderate–severe CKD (Stage III-V; eGFR60 ml/min). RESULTS: 17% of patients revealed a baseline eGFR0.05). Concerning tumor characteristics, there was no difference in tumor size, but patients with mild or normal CKD had higher PADUA scores (9 vs. 8; p 60 ml/min (43% vs. 34%; p=0.002). However, major complications (Clavien Dindo>2 ) occurred more often in patients with limited kidney function (10% vs. 7%; p0.05). Patients with eGFR<59 ml/min remained higher proportion of acute kidney failure according to RIFLE criteria (risk: 26% vs. 20%; injury: 4% vs. 2%, failure: 3% vs. 0.3%; p<0.001). MIC criteria (negative margins, ischemia time<20 minutes, no major complications) were achieved in the majority of patients without differences between both groups (75% vs. 79%; p=0.112). CONCLUSIONS: RAPN is a good option for patients with lower baseline eGFR. The renal function loss stays within tolerable ranges. To set realistic patient expectations, this patient group should be informed preoperatively about a higher risk for perioperative complications. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e731 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Olga Katzendorn More articles by this author Christian Fuhrmann More articles by this author Frank Schiefelbein More articles by this author Georg Schoen More articles by this author Clemens Wiesinger More articles by this author Jacob Pfuner More articles by this author Burkhard Ubrig More articles by this author Simon Gloger More articles by this author Philipp Nuhn More articles by this author Ahmed Eraky More articles by this author Christian Wagner More articles by this author Abdirahman Ayanle More articles by this author Claudia Kesch More articles by this author Mulham Al-Nader More articles by this author Boris A. Hadaschik More articles by this author Pouriya Faraj Tabrizi More articles by this author Markus A. Kuczyk More articles by this author Stefan Siemer More articles by this author Michael Stöckle More articles by this author Philip Zeuschner More articles by this author Nina N. Harke More articles by this author Expand All Advertisement PDF downloadLoading ...