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Germ cell tumors rarely present in the anterior mediastinum. We report a case of 43-year-old female who presented to the hospital with cough and chest pain. Computed tomography imaging showed a 7.8 cm right anterior mediastinal mass with extension to the right upper lung. A tissue biopsy was performed showing organizing fibrosis and granulomatous inflammation, scattered foreign body type multinucleated giant cells, and rare non-necrotizing epithelioid granuloma. The patient underwent complete mass resection with the da Vinci Xi® robotic surgical system (Intuitive Surgical, Inc., Sunnyvale, CA, USA). Surgical histopathology of the mass revealed benign mediastinal mature teratoma.
Hsiung et al. (2024) studied this question.