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November 24, 2025Cureus0 citationsOpen Access

Artificial Intelligence in Bone Fracture Detection: A Review of Evidence, Limitations, and Clinical Integration

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AEAhmed ElkohailASAli SoffarAPAshis Kumar Paul

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Abstract

Medical imaging is rapidly being improved by artificial intelligence (AI), with deep-learning systems performing well in radiography, CT, and MRI for fracture detection, classification, and localization. This narrative review examined recent evidence spanning different types of bone fractures, alongside soft-tissue injuries relevant to orthopedic decision-making. Across multiple meta-analyses and external validations, reported sensitivities and specificities commonly range from 0.85 to 0.95, while AI also supports workflow triage and reader confidence. Persistent gaps include limited generalizability, inconsistent reference standards, spectrum bias, regulatory and ethical challenges, and implementation costs. We outline pragmatic quality considerations and emphasize prospective, multi-center trials and transparent reporting for safe clinical integration. AI should augment clinicians, improving speed, accuracy, and overall patient outcomes.

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Elkohail et al. (2025) studied this question.

synapsesocial.com/papers/69403b952d562116f290c583https://doi.org/10.7759/cureus.97674
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1AI-Assisted Fracture Detection in Orthopedic and Trauma Imaging: Where It Works, Where It Fails, and Principles for Safe Clinical Deployment2026
  2. 2Incorporating Artificial Intelligence into Fracture Risk Assessment: Using Clinical Imaging to Predict the Unpredictable2025
  3. 3APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN IMAGING-BASED DIAGNOSIS OF ORTHOPEDIC INJURIES2025
  4. 4Artificial Intelligence in Fracture Detection: Current Capabilities, Clinical Impact, and Future Directions2026
  5. 5Advancing Spine Fracture Detection: The Role of Artificial Intelligence in Clinical Practice2025 · 3 citations