Purpose: To systematically evaluate the effect of different centration methods on postoperative visual quality in patients with refractive error undergoing corneal refractive surgery. Methods: Overall, 3,140 eyes from 65,604 records were retrieved through a comprehensive search of eight databases. Thirteen studies were included in the meta-analysis to evaluate the impact of centration methods on visual quality outcomes. Results: Postoperative decentration was significantly lower in the coaxially sighted corneal light reflex (CSCLR)–centered group than in the entrance pupil center (EPC)–centered group ( P .05). Induced coma was significantly lower in the CSCLR-centered group ( P .05). Conclusions: CSCLR centration ablation might have a potential advantage over EPC centration in achieving better postoperative outcomes (SE residuals, and induced coma) after corneal refractive surgery according to the currently available low-quality evidence. When the preoperative angle kappa is large, an angle kappa adjustment is suggested. More high-quality trials are required in future research.
Xu et al. (Thu,) studied this question.
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