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January 16, 2026Microbiology0 citationsOpen Access

Antimicrobial and anti-inflammatory properties of Maranta arundinacea extract against Campylobacter jejuni and Campylobacter coli in T84 cells

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BSBanaz Star-ShirkoNCNicolae CorcionivoschiOGOzan Gundogdu

Key Points

  • This research aims to assess the antimicrobial and anti-inflammatory effects of Maranta arundinacea extract against Campylobacter strains in T84 cells.
  • Evaluated the cytotoxicity of Maranta arundinacea extract in T84 cells at various concentrations.
  • Measured bacterial growth reduction in Campylobacter jejuni and Campylobacter coli strains after treatment with the extract.
  • Statistical analysis of growth inhibition effects at different concentrations.
  • 4% and 25% concentrations of arrowroot extract showed no cytotoxicity in T84 cells.
  • Significant reduction in bacterial growth was observed for Campylobacter jejuni at tested concentrations.
  • The extract also inhibited Campylobacter coli and Escherichia coli, with significant effects noted at 25% concentration.

Abstract

Campylobacter , a bacterium commonly found in the chicken gut, is the leading cause of bacterial foodborne gastroenteritis globally. Despite various interventions aimed at controlling Campylobacter in the food chain, such as enhanced biosecurity measures, improved hygiene practices and farm-level controls, reducing its prevalence remains a significant challenge. While the European Union’s (EU) 2006 ban on antimicrobials as growth promoters was primarily intended to control antimicrobial resistance, its impact on Campylobacter load has been limited. The emergence of antibiotic-resistant Campylobacter has created a requirement to develop alternative methods to improve food safety, enhance performance and mitigate pathogenic bacteria. This study explored the potential of Maranta arundinacea (arrowroot) extract as a prospective dietary supplement for both humans and chickens. The investigation focused on its safety, its ability to reduce Campylobacter in T84 intestinal epithelial cells and its anti-inflammatory properties. Results showed that 4% and 25% concentrations of arrowroot extract were non-cytotoxic to human T84 cells and significantly reduced bacterial growth in Campylobacter jejuni strains. Additionally, the extract inhibited the growth of Campylobacter coli strains and Escherichia coli , with statistical significance observed against E. coli at the 25% concentration. These results suggest that arrowroot extract could be a promising natural alternative for addressing antibiotic resistance and enhancing food safety.

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Cite This Study

Star-Shirko et al. (2026) studied this question.

synapsesocial.com/papers/6969d4c3940543b977709a8ahttps://doi.org/10.1099/mic.0.001658
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