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January 17, 2026RSC AdvancesOpen Access

HDAC inhibitors as anticancer drugs: chemical diversity, clinical trials, challenges and perspectives

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Authors

AAA. AbdAllah

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Overview

Clinical data compare HDAC inhibitors' structural features to enhance anticancer therapies, suggesting new possibilities.

Key Points

  • The research aims to analyze clinical data on HDAC inhibitors to understand their effectiveness in cancer treatment.
  • Collected data from clinical trials involving HDAC inhibitors.
  • Compared various structural features of these compounds.
  • Analyzed the impact of those features on anticancer efficacy.
  • Identified key structural features that affect the efficacy of HDAC inhibitors.
  • Revealed limitations and challenges faced in clinical applications.
  • Suggested pathways for improving future cancer therapies using HDAC inhibitors.

Cite This Study

A. AbdAllah (2026) studied this question.

synapsesocial.com/papers/696b25a9d2a12237a93490b2https://doi.org/10.1039/d5ra09034b
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