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January 17, 2026Scientific Reports0 citationsOpen Access

Skin disease diagnostics through federated transfer learning on heterogeneous data

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SSShikha SharmaRMRuchi MittalNGNitin Goyal

Key Points

  • The aim is to improve diagnostic accuracy for skin diseases using federated transfer learning while maintaining data privacy.
  • Implemented federated transfer learning to enhance model training across distributed nodes.
  • Utilized dense neural networks for skin disease detection and classification.
  • Applied feature extraction through pre-trained architectures for improved model efficiency.
  • Tested model performance on both IID and non-IID datasets.
  • Achieved cross-validation accuracy of 99.528% on IID and 99.689% on non-IID databases.
  • Demonstrated the ability to create lightweight models suitable for resource-constrained devices.
  • Highlighted the effectiveness of ensemble learning in enhancing performance on edge devices.

Abstract

Abstract Skin diseases frequently cause mental and physical distress and are major global health concern. Because early detection is crucial to successful treatment, accurate diagnosis is challenge for dermatologists as well. Diagnostic accuracy could be significantly enhanced using methods like machine learning (ML) and deep learning (DL). However, substantial datasets are required for these models to make accurate predictions. The healthcare providers frequently encounter data shortages, and privacy regulations restrict data sharing. A privacy-preserving federated transfer learning for diagnosing skin diseases which incorporate four key strategies to enhance effectiveness. The transfer learning is used to train a model with dense neural network (DNN) for skin diseases detection. The feature extraction is performed using pre-trained architectures and DNN is used for classification. The federated learning (FL) replaces the transfer learning to train the model across distributed nodes with the DNN used to disease detection. The FL is combined with transfer learning to build a cohesive ecosystem where data privacy is maintained. The model performance was validated on both IID and non-IID database, with the proposed feature extraction with federated learning model achieving cross validation accuracy of 99.528% and 99.689% for IID and non-IID database, respectively. Results indicate that feature extraction with FL model can produce efficient, lightweight models—well-suited for resource-constrained devices—while ensemble learning enhances edge device performance, offering a powerful and privacy-preserving solution for skin disease diagnosis in modern healthcare.

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Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/696b25cfd2a12237a9349198https://doi.org/10.1038/s41598-025-31730-7
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