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January 17, 2026RSC Advances3 citationsOpen Access

CHA-driven SERS-nanoenzyme sensor for ultra-sensitive diagnosis of gastric precancerous lesions

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YHYa HuangYZYanwen ZhuangMZMiao Zhu

Key Points

  • This research aims to develop a sensitive sensor for the early detection of gastric precancerous lesions.
  • Developed a SERS (Surface-Enhanced Raman Spectroscopy) nanoenzyme sensor driven by carbohydrate-based molecules.
  • Tested the sensor for its sensitivity and specificity in detecting precancerous lesions.
  • Conducted comparative analyses with existing diagnostic methods.
  • The sensor showed ultra-sensitive detection of gastric precancerous lesions.
  • It significantly outperformed traditional diagnostic methods in sensitivity.

Abstract

Early identification and timely intervention of precancerous lesions of gastric cancer are the core strategies to block their malignant transformation into gastric cancer (GC).

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Cite This Study

Huang et al. (2026) studied this question.

synapsesocial.com/papers/696b25f3d2a12237a93493a4https://doi.org/10.1039/d5ra07186k
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