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January 18, 2026Journal of Clinical MedicineOpen Access

Radioguided Localisation Techniques for Non-Palpable Breast Lesions: An Umbrella Review

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Authors

MCMarco CuzzocreaCICesare Michele IacovittiNPNickolas Peradze

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Overview

This umbrella review compares radioguided localisation techniques with wire-guided localisation in non-palpable breast lesions, indicating improved outcomes.

Key Points

  • This review aims to synthesize evidence regarding the efficacy and safety of radioguided localisation techniques for non-palpable breast lesions compared to wire-guided localisation.
  • Comprehensive literature search conducted on PubMed/Medline and Cochrane Library
  • Focus on systematic reviews and meta-analyses published until 2024
  • Assessment of outcomes like margin positivity and re-excision rates
  • Radioguided techniques showed high localisation success rates, often exceeding 95%
  • Fewer positive margins were observed with radioguided methods compared to wire-guided localisation
  • Operative times were generally shorter for radioguided techniques with comparable safety profiles

Cite This Study

Cuzzocrea et al. (2026) studied this question.

synapsesocial.com/papers/696c774feb60fb80d13958c1https://doi.org/10.3390/jcm15020750
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