Phenotypic plasticity drives adaptation in evolution and cancer, viewed through systems biology and Whitehead’s process philosophy as a dynamic, relational process. Critiquing gene-centric reductionism, it integrates tissue-based dynamics, processual biology, and network science to address drug tolerance and metastasis. Emphasizing information processing and chaotic dynamics, this framework proposes novel therapies, inviting experimental validation to advance health outcomes.
Mesut Tez (2025) studied this question.