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January 20, 20260 citations

Reversible Pseudo-Amyloid Strain Pattern in Acute Hypertensive Cardiomyopathy.

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EDEdward DababnehDYDylan YoungMMMaría Gabriela Matta

Key Result

Acute hypertensive cardiomyopathy can produce a rapidly reversible pseudo-amyloid strain pattern with apical sparing that mimics amyloidosis.

Key Points

  • The research aims to differentiate reversible patterns of strain in acute hypertensive cardiomyopathy that resemble amyloid disease.
  • Analysis of strain patterns in patients with acute hypertensive cardiomyopathy.
  • Evaluation of apical sparing and basal dysfunction characteristics.
  • Assessment of diagnostic reversibility in strain patterns.
  • Identified apical sparing as a significant feature in acute hypertensive cardiomyopathy.
  • Observed that load-dependent basal dysfunction can mimic amyloid strain patterns.
  • Demonstrated that rapid reversibility aids in distinguishing between conditions.

Structured PICO

P
Population
Patients with acute hypertensive cardiomyopathy

Acute hypertensive cardiomyopathy can present with a reversible pseudo-amyloid strain pattern on echocardiography, which must be distinguished from true cardiac amyloidosis.

Abstract

Apical sparing can occur in acute hypertensive cardiomyopathy. Load-dependent basal dysfunction may mimic amyloid patterns. Rapid reversibility aids diagnostic distinction.

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Cite This Study

Dababneh et al. (2026) studied this question. Acute hypertensive cardiomyopathy can produce a rapidly reversible pseudo-amyloid strain pattern with apical sparing that mimics amyloidosis.

synapsesocial.com/papers/696f1a239e64f732b51ee6a6https://doi.org/10.1016/j.jaccas.2025.106717
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