Why the study?
Nurse-led clinics can potentially provide effective secondary prevention for CHD, prompting an updated systematic review to determine their effectiveness on mortality, morbidity, and other clinical and patient outcomes.
Do nurse-led clinics reduce mortality and morbidity in adults with coronary heart disease compared to usual care?
Comparison
Nurse-led clinics vs usual care by another healthcare professional
Design
Systematic review and meta-analysis of randomized controlled trials
Key result
Nurse-led clinics for adults with coronary heart disease resulted in no significant difference in mortality (RR 0.91; 95% CI 0.59-1.40; P=0.67) but slightly reduced CHD exacerbations.
Authors
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Supports nurse-led clinics for CHD secondary prevention to cut exacerbations; strengthens RCT meta-analytic evidence without mortality benefit.
Meta-Analysis
Do nurse-led clinics reduce mortality and morbidity in adults with coronary heart disease compared to usual care?
Relative Risk: 0.91 (95% CI 0.59–1.4)
p-value: p=0.67
Nurse-led clinics for secondary prevention of coronary heart disease effectively reduce CHD exacerbations and improve risk factor management and medication adherence compared to usual care.
Alzhanova et al. (2025) conducted a meta-analysis in Coronary heart disease. Nurse-led clinics vs. Usual care by another healthcare professional was evaluated on Mortality (RR 0.91, 95% CI 0.59-1.40, p=0.67). Nurse-led clinics for adults with coronary heart disease resulted in no significant difference in mortality (RR 0.91; 95% CI 0.59-1.40; P=0.67) but slightly reduced CHD exacerbations.