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January 20, 20262 citations

Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease.

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YYYuanhang YangACAntoine CréonALAndrew S. Levey

Key Points

  • The study aims to explore the association between population-based eGFR values and health outcomes related to chronic kidney disease.
  • Analyzed population-based eGFR values
  • Established distribution percentiles
  • Examined associations with kidney failure and mortality rates
  • eGFR values below the 25th percentile correlate with higher risks of kidney failure
  • Lower eGFR is associated with increased mortality rates
  • Population-based eGFR charts can enhance current reporting systems for early identification

Abstract

Our study shows that eGFR values below the 25th percentile of the population distribution are associated with increased risks of kidney failure and death. Population-based eGFR charts may complement current automatic reporting systems and provide opportunities for early identification and primary prevention of CKD.

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/696f1b189e64f732b51ef236https://doi.org/10.1016/j.kint.2025.11.009
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