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January 22, 2026Organic & Biomolecular Chemistry0 citations

A Hexadentate Co(III) Catalyst Enables One-Pot Quinazolinone Synthesis via Metal–Ligand Cooperative Alcohol Activation

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PKPrashant KukretiTPTanya PatnaikRCRahul Chauhan

Key Points

  • This research aims to demonstrate a new method for synthesizing quinazolinones using a Co(III) catalyst.
  • Developed a hexadentate Co(III) catalyst
  • Utilized acceptorless dehydrogenation of primary alcohols
  • Conducted reactions under air-stable conditions
  • Achieved efficient quinazolinone synthesis
  • Demonstrated metal-ligand cooperative activation
  • Showed potential for broader applications in organic synthesis

Abstract

Here, we present the first Co(III) catalysed efficient metal ligand cooperative route for the synthesis of quinazolinone using acceptorless dehydrogenation of primary alcohols. An air-stable phosphine-free Co(III) complex anchored by...

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Cite This Study

Kukreti et al. (2025) studied this question.

synapsesocial.com/papers/6971bd90642b1836717e23b5https://doi.org/10.1039/d5ob01916h
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