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January 22, 2026Open Access

A Thermodynamic Deep Dive into the Etiology of Neurosis

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Authors

HCHugo Evaristo Tapia Castañeda

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Overview

This theoretical analysis links thermodynamics to neurobiology, highlighting a new perspective on neurosis etiology.

Key Points

  • To explore the biological underpinnings of neurosis through a thermodynamic lens and genomic analysis.
  • Theoretical extension of neurosis etiology focusing on SRGAP2C gene duplication.
  • Analysis of synaptic density and its impact on DMN and TPN interaction.
  • Application of information thermodynamics and Kullback-Leibler divergence to measure cognitive states.
  • Development of a Translational Human Engineering protocol utilizing Immersive VR and rTMS.
  • Quantified cognitive metastability indicating systemic failure in neuronal processes.
  • Identified biomarkers linked to existential inflammation, including Interleukin-6 and ccf-mtDNA.

Cite This Study

Hugo Evaristo Tapia Castañeda (2026) studied this question.

synapsesocial.com/papers/6971bd90642b1836717e23c5https://doi.org/10.5281/zenodo.18318968
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