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January 22, 2026Chemical Science0 citationsOpen Access

Radical docking-migration: a powerful strategy for difunctionalization of alkenes and alkynes

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ZCZhu CaoFCFushan CHENCZChen Zhu

Key Points

  • To explore a radical-mediated approach for the difunctionalization of alkenes and alkynes.
  • Utilized radical-mediated processes to add functional groups to alkenes and alkynes.
  • Employed the docking-migration strategy for effective molecular transformations.
  • Analyzed the efficiency of producing complex architectures from unsaturated precursors.
  • Successfully demonstrated the construction of complex molecular architectures.
  • Achieved high efficiency in the difunctionalization process.
  • Provided a robust method for functionalizing simple unsaturated compounds.

Abstract

Radical-mediated difunctionalization of alkenes and alkynes represents a powerful and efficient strategy for constructing complex molecular architectures from simple unsaturated precursors. The docking-migration approach, which involves the initial addition of...

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Cite This Study

Cao et al. (2026) studied this question.

synapsesocial.com/papers/6971bd90642b1836717e23d1https://doi.org/10.1039/d5sc08771f
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