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January 23, 20260 citations

Evaluation of Soluble ST2 and Galectin-3 Levels in Patients with Heart Failure.

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MÇMustafa ÇetınZTZülkif TanrıverdiRDRecep Demirbağ

Key Points

  • This research aims to evaluate the levels of soluble ST2 and galectin-3 in heart failure patients to understand their significance as biomarkers.
  • Comparative analysis of soluble ST2 and galectin-3 levels in heart failure patients and a control group.
  • Assessment categorized by heart failure types: HFrEF, HFmrEF, and HFpEF.
  • Statistical evaluation of biomarker levels in relation to ejection fraction.
  • Both soluble ST2 and galectin-3 levels were significantly higher in patients with HFrEF and HFmrEF compared to the control group.
  • As ejection fraction decreased, levels of soluble ST2 and galectin-3 increased.
  • No significant difference was found in these markers between patients with HFpEF and controls.

Abstract

sST2 and galectin-3 levels were higher in patients with HFrEF and HFmrEF compared to the control group, and these markers increased as EF decreased. However, these markers did not differ between patients with HFpEF and the control group.

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Cite This Study

Çetın et al. (2026) studied this question.

synapsesocial.com/papers/69730f59c8125b09b0d1f1bahttps://doi.org/10.5543/tkda.2025.44679
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