Objective: We report changes in the Crohn’s Disease Activity Index (CDAI) and clinical outcomes after Korean medicine treatment, including Gami-Guibi-tang and acupuncture, in a patient with active Crohn’s disease.Methods: A 49-year-old male with recurrent bleeding despite upadacitinib 15 mg once daily presented to our clinic in March 2025.Results: The CDAI decreased from 230 at baseline (2025-03-07) to 60 by 2025-09-15. After initiation of Gami-Guibi-tang on 2025-07-10 with weekly acupuncture, hematochezia resolved and abdominal pain (VAS) improved. No adverse events were observed.Conclusion: Korean medicine treatment centered on Gami-Guibi-tang may contribute to improvement in disease activity in patients with active Crohn’s disease with bleeding.
Yu et al. (2025) studied this question.