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January 23, 2026Journal of Crohn s and Colitis

P1275 Tuberculosis screening results of Inflammatory Bowel Disease patients from a Romanian Tertiary Center

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Authors

OMO M MuruCPC S PopNTNicoleta Tiucă

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Overview

Finds high rates of latent tuberculosis in inflammatory bowel disease patients, indicating urgent screening needs.

Key Points

  • The aim is to assess the prevalence of latent tuberculosis in patients with inflammatory bowel disease at a Romanian tertiary center.
  • Retrospective analysis of patients with inflammatory bowel disease treated at a tertiary hospital from 2000 to 2025.
  • Demographic and clinical data collected from patient files.
  • Screening for latent tuberculosis using the QuantiFERON-TB Gold Test.
  • Sputum RT-PCR test performed for symptomatic patients.
  • 83.06% of the 124 patients screened tested positive for latent tuberculosis.
  • Only 2 patients had a known history of active tuberculosis.
  • The majority had ulcerative colitis, were men, and exhibited multiple comorbidities.
  • During a 25-year follow-up, only 4 patients developed active tuberculosis while on biological therapy.

Cite This Study

Muru et al. (2026) studied this question.

synapsesocial.com/papers/69731005c8125b09b0d1fc58https://doi.org/10.1093/ecco-jcc/jjaf231.1456
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