Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 23, 2026Journal of Crohn s and Colitis

P1304 Mild Crohn’s disease in Sri Lanka: a nationwide study

View Full Paper
Ask AI
Bookmark
Share

Authors

MNMadunil Anuk NiriellaHJHiruni JayasenaNWNimali Wanniarachchi

Discussion

Loading...

Member takes

Overview

A nationwide study observes mild Crohn's disease, characterizing presentation and outcomes in Sri Lanka, indicating favorable progression.

Key Points

  • To characterize the clinical presentation and outcomes of patients with mild Crohn's disease in Sri Lanka.
  • Conducted a prospective, multicentre study across Sri Lanka from January to October 2025.
  • Enrolled patients diagnosed with mild Crohn's disease defined by specific criteria (age of onset >30 years, aphthoid ulcers on endoscopy).
  • Collected data on demographics, disease location and behavior, laboratory parameters, and treatment patterns.
  • Followed up patients for at least 12 months to assess disease progression.
  • Mild Crohn's disease was found in only 5 patients (7.0%) among 215 patients diagnosed with Crohn's disease.
  • Predominantly affected females (67.7%) with a mean age of onset of 40.53 years.
  • Colonic involvement was seen in 86.6% of mild cases, with some ileal involvement (46.6%).
  • Weight loss and altered bowel habits were reported by all patients, while extraintestinal manifestations were absent (0.0%).
  • 26.7% of patients progressed to moderate-severe Crohn's disease over the follow-up period, primarily in those treated with biologics.

Cite This Study

Niriella et al. (2026) studied this question.

synapsesocial.com/papers/69731047c8125b09b0d1ff1bhttps://doi.org/10.1093/ecco-jcc/jjaf231.1485
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P0221Long-term Outcomes and Predictors of Indolent Course in Newly Diagnosed Mild Crohn’s Disease: A Retrospective Cohort Study2026
  2. 2P0917Clinical, Endoscopic, Radiologic, and Therapeutic Profile of Perianal Crohn’s Disease: Insights from a Real-World Indian Cohort (iGONDOMAR-India study group)2026
  3. 3P1199The epidemiological profil of patients with Inflammatory Bowel Disease2026 · 1 citations
  4. 4P0316Natural History of Newly Diagnosed Mild Crohn’s Disease: Risk of Progression and Predictors in an Italian Multicentre Cohort2026
  5. 5P1297 Prevalence and epidemiological features of adult upper gastrointestinal Crohn’s disease over the last 30 years: A scoping review2026