Effect of Perinatal Multiple Exposures to Heavy Metals and Dioxins on Serum Steroids in Preschool Children—A Follow‐Up Study in an E‐Waste Contaminated Area in China
Follow-up study finds that perinatal exposure to heavy metals and dioxins affects serum steroid hormone levels in children, indicating potential health risks.
Key Points
This research aims to assess the impact of perinatal exposure to heavy metals and dioxins on serum steroid levels in preschool children.
Assessing children from an e-waste polluted area
Collecting breast milk and blood samples
Analyzing using multivariable linear regression and Bayesian kernel machine regression models
Investigating steroid hormones and pollutants in biological samples
Total polychlorinated dibenzofurans (PCDFs) negatively associated with DHEA levels
Cadmium (Cd) showed a negative association with progesterone
2,3,7,8-TeCDD positively associated with DHEA levels
Associations were attenuated in Bayesian kernel machine regression results