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January 24, 2026Bioinformatics0 citationsOpen Access

Uchimata: a toolkit for visualization of 3D genome structures on the web and in computational notebooks

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DKDavid KouTMTrevor ManzTCTereza Clarence

Key Points

  • The aim is to provide tools for visualizing 3D genome structures for better understanding and interpretation.
  • Developed a Javascript library for 3D genome modeling.
  • Created a Python widget for use in Jupyter Notebooks.
  • Incorporated visual encodings and filtering based on genomics.
  • Uchimata enables flexible visualization of complex genomic data.
  • Improves accessibility and integration with existing biological tools in Python.

Abstract

Abstract Summary Uchimata is a toolkit for visualization of 3D structures of genomes. It consists of two packages: a Javascript library facilitating the rendering of 3D models of genomes, and a Python widget for visualization in Jupyter Notebooks. Main features include an expressive way to specify visual encodings, and filtering of 3D genome structures based on genomic semantics and spatial aspects. Uchimata is designed to be highly integratable with biological tooling available in Python. Availability and Implementation Uchimata is released under the MIT License. The Javascript library is available on NPM, while the widget is available as a Python package hosted on PyPI. The source code for both is available publicly on Github (https://github.com/hms-dbmi/uchimata and https://github.com/hms-dbmi/uchimata-py) and Zenodo (https://doi.org/10.5281/zenodo.17831959 and https://doi.org/10.5281/zenodo.17832045). The documentation with examples is hosted at https://hms-dbmi.github.io/uchimata/

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Cite This Study

Kou et al. (2026) studied this question.

synapsesocial.com/papers/69746149bb9d90c67120b339https://doi.org/10.1093/bioinformatics/btag035
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