Potential Enhancement of Topical Drug Delivery Using Grapefruit-derived Nanoparticles Modified Using TAT Peptide.

Puntos clave

• The aim is to improve the skin penetration of drug delivery systems using grapefruit-derived nanoparticles.
• Mixing procedure to combine grapefruit-derived nanoparticles with STR-Tat peptide.
• Assessment of skin penetration ability using a lipophilic dye.
• Evaluation of cellular toxicity to confirm safety of the approach.
• Enhanced skin penetration ability of the lipophilic dye associated with nanoparticles.
• No cellular toxicity from the modified nanoparticles.