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January 24, 20260 citationsOpen Access

Feasibility of tumor-informed circulating tumor DNA for detecting minimal residual disease in surgically resected biliary tract cancer.

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YPYOUNGHEE PARKJNJi Ho NamHJHyunji Jo

Key Points

  • The aim is to evaluate the feasibility of using tumor-informed circulating tumor DNA (ctDNA) for detecting minimal residual disease (MRD) in biliary tract cancer.
  • Analyzed tumor-informed ctDNA samples from patients with resected biliary tract cancer.
  • Assessed the potential of ctDNA as a biomarker for identifying MRD.
  • Considered limitations due to small sample size.
  • Results suggest a potential role for ctDNA in MRD detection.
  • The findings indicate a need for larger studies to validate these results.

Abstract

Although limited by the small sample size, our results may indicate a possible role for tumor-informed ctDNA analysis in detecting MRD in surgically resected BTC and warrant further validation in larger studies.

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Cite This Study

PARK et al. (2026) studied this question.

synapsesocial.com/papers/69746187bb9d90c67120b6cehttps://doi.org/10.1371/journal.pone.0341432
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