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January 24, 2026Wiley Interdisciplinary Reviews Cognitive Science0 citationsOpen Access

The Inverted U: Exploring the Interconnectedness of Movement and Cognitive Function Across the Lifespan

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GLGerry LeismanRARahela AlfasiOMOded Meiron

Key Points

  • This study explores the relationship between physical activity levels and cognitive function across the human lifespan.
  • Analyzed the inverted U relationship between movement and cognition from fetal development to old age.
  • Examined the effects of maternal physical activity on fetal brain development.
  • Assessed cognitive improvements linked to regular physical activity during childhood and adulthood.
  • Investigated the role of physical activity in reducing neurodegenerative disease risks in older adults.
  • Optimal cognitive function is achieved at moderate levels of physical activity.
  • Insufficient physical activity leads to decreased cognitive outcomes in various life stages.
  • Regular physical activity supports attention, memory, and executive functions in children.
  • Active lifestyles in adulthood and older age preserve cognitive abilities and enhance quality of life.

Abstract

ABSTRACT The “inverted U” relationship between movement and cognition throughout the human lifespan highlights the intricate interplay between physical activity and cognitive function. This relationship posits that an optimal level of physical activity maximizes cognitive function, while insufficient activity can lead to suboptimal cognitive outcomes. This phenomenon is observed from fetal development to old age, emphasizing the importance of maintaining a balance in physical activity for overall well‐being. During fetal development, maternal physical activity positively influences fetal brain growth, laying the foundation for future cognitive and physical functioning. As the child develops, regular physical activity supports improvements in key cognitive functions such as attention, memory, and executive function abilities essential for learning and academic success. In adulthood, maintaining an active lifestyle continues to play a central role in preserving cognitive abilities and reducing the risk of neurodegenerative diseases such as Alzheimer's. The inverted U model suggests that optimal cognitive functioning is achieved at moderate levels of physical activity, while too little activity can be detrimental. In older adulthood, regular physical activity is vital for maintaining cognitive function, slowing cognitive decline, and improving quality of life. In summary, understanding the balance between physical activity and cognition across the lifespan is essential for promoting cognitive resilience and sustained well‐being. This article is categorized under: Cognitive Biology > Cognitive Development Psychology > Development and Aging Psychology > Learning

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Cite This Study

Leisman et al. (2026) studied this question.

synapsesocial.com/papers/697461a8bb9d90c67120b7b9https://doi.org/10.1002/wcs.70020
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