Decoding the neural basis of olfactory dysfunction: a multimodal MRI study in CRS-OD.

Key Points

• The study aims to explore the neural underpinnings of olfactory dysfunction in chronic rhinosinusitis (CRS).
• Utilized multimodal MRI techniques
• Assessed olfactory bulb (OB) and gray matter changes
• Examined functional connectivity patterns
• Identified atrophy in olfactory bulbs
• Observed gray matter atrophy in related regions
• Found disrupted functional connectivity reflecting neural alterations