Summary Continuous wound infusion with local anaesthetics after open abdominal surgery may provide opioid‐sparing analgesia, but evidence on very low‐concentration regimens is limited. We conducted a prospective observational study including 50 patients receiving continuous infusion of levobupivacaine 0.0625% via pre‐peritoneal or subfascial catheters at a flow rate of 12 ml.h −1 per catheter. Six patients (12%) required intravenous morphine rescue in the first 48 h, with a median dose of 3 mg. Median pain scores remained consistently low and 14 patients (28%) received additional local anaesthetic boluses with effective relief. No major catheter‐related complications or systemic local anaesthetic toxicity were observed. Continuous wound infusion with levobupivacaine 0.0625% after open abdominal surgery was feasible and associated with minimal opioid use. These findings provide preliminary evidence supporting the feasibility of an ultralow concentration regimen.
Zamudio et al. (2026) studied this question.