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January 26, 20260 citations

Endovascular Repair in High-Risk Uncomplicated Type B Aortic Dissection: A Systematic Review and Single-Arm Meta-Analysis.

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MJMilton Sérgio Bohatch JúniorBSBeatriz de Melo SilvaESElisabeth Amanda Gomes Soares

Key Points

  • To evaluate the safety and effectiveness of thoracic endovascular aortic repair in high-risk uncomplicated type B aortic dissection.
  • Conducted a systematic review
  • Performed a single-arm meta-analysis
  • Analyzed non-randomized studies concerning outcomes
  • Examined early mortality and long-term survival
  • Low early mortality observed in the cohort
  • Favorable long-term survival associated with TEVAR
  • Encouraging outcomes in aortic remodeling noted
  • Identified potential complications like stroke and spinal cord ischemia

Abstract

Thoracic endovascular aortic repair in hrTBAD patients is associated with low early mortality and favorable long-term survival and aortic remodeling, especially when performed during the subacute phase. Despite encouraging results, current evidence is limited to non-randomized studies. Further prospective trials are needed to refine patient selection and determine long-term efficacy.Clinical ImpactThis meta-analysis reinforces that thoracic endovascular aortic repair (TEVAR) for high-risk uncomplicated type B aortic dissection (hrTBAD) is safe and potentially beneficial, demonstrating low early mortality and encouraging aortic remodeling outcomes. However, the procedure is not devoid of complications, such as stroke, spinal cord ischemia, stent-induced new entry (SINE), or retrograde dissection, which may be infrequent in conservatively managed patients. Until randomized evidence becomes available, TEVAR should be considered on a case-by-case basis, integrating anatomical risk profiles, institutional expertise, and individualized prognostic assessment within multidisciplinary decision-making.

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Cite This Study

Júnior et al. (2026) studied this question.

synapsesocial.com/papers/697703f6722626c4468e8eb2https://doi.org/10.1177/15266028251408978
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