Renal-artery denervation did not result in a significant reduction of systolic blood pressure compared to sham control in patients with resistant hypertension after 6 months.
Does renal-artery denervation reduce systolic blood pressure in patients with resistant hypertension?
Renal-artery denervation failed to significantly reduce systolic blood pressure compared to a sham procedure in patients with resistant hypertension.
This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control. (Funded by Medtronic; SYMPLICITY HTN-3 ClinicalTrials.gov number, NCT01418261.).
“A decade later, renal denervation has re-emerged with stronger evidence, refined technique and renewed clinical relevance.”
Bhatt et al. (2014) studied this question. Renal-artery denervation did not result in a significant reduction of systolic blood pressure compared to sham control in patients with resistant hypertension after 6 months.