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February 2, 2026Haematologica0 citationsOpen Access

Myelodysplastic syndrome with cryptic 5q deletions in young male patients showing sustained response to lenalidomide

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WNWala NajarLBLauren BaretteDPDominique Penther

Key Points

  • The aim is to investigate the response to lenalidomide in young male patients with myelodysplastic syndrome and cryptic 5q deletions.
  • Provided treatment with lenalidomide
  • Monitored hematologic responses
  • Conducted cytogenetic analyses to identify 5q deletions
  • Patients showed significant hematologic response to lenalidomide treatment
  • Cryptic 5q deletions were confirmed in young male patients
  • Response was sustained over a defined treatment duration

Abstract

Not available.

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Cite This Study

Najar et al. (2026) studied this question.

synapsesocial.com/papers/6980fcb6c1c9540dea80e7f6https://doi.org/10.3324/haematol.2025.288855
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Myelodysplastic syndrome with concomitant SF3B1 mutation and deletion of chromosome 5 long arm: outcomes and response to treatment2026
  2. 2Myelodysplastic syndrome (MDS)/Myeloproliferative neoplasm (MPN) with loss of long arm of chromosome 5 (del 5q): Clinical case and treatment perspectives.2024
  3. 3Myelodysplastic Disease Associated with Deletions of Chromosome 5q Region2025
  4. 4Real-world utilization and outcomes of lenalidomide in MDS with low blasts and isolated deletion 5q (MDS w 5q).2026
  5. 5Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide2024 · 14 citations