The study aims to develop a dual-mode biosensor for the detection of methotrexate using fluorescence resonance energy transfer (FRET) and UV absorption techniques.
Developed a dual-mode biosensor for methotrexate detection.
Utilized FRET technology for sensitivity enhancement.
Incorporated silver nanoparticles (Ag NPs) to improve UV absorption detection.
Demonstrated effective detection of methotrexate with high sensitivity.
Achieved synergistic effects combining FRET and UV absorption for better detection performance.
Abstract
A synergistic dual-mode biosensor for methotrexate detection leveraging FRET and Ag NPs based UV absorption.