Correction: Xu et al. Notch1 Protects Against Ischemic-Reperfusion Injury by Suppressing PTEN-Pink1-Mediated Mitochondrial Dysfunction and Mitophagy. Cells 2023, 12, 137

Key Points

• The research focuses on understanding how Notch1 protects cells from ischemic-reperfusion injury by affecting mitochondrial functions.
• Examined the role of Notch1 in cellular responses to ischemic-reperfusion injury.
• Analyzed mitochondrial dysfunction using various biochemical assays.
• Investigated the relationship between PTEN, Pink1, and mitochondrial health in the context of Notch1 signaling.
• Notch1 activation significantly reduces the severity of ischemic-reperfusion injury.
• Inhibition of PTEN enhances Pink1 activity, improving mitochondrial function.
• Cells with activated Notch1 showed lower levels of mitophagy markers compared to controls.