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February 2, 2026npj Mental Health Research1 citationsOpen Access

Accelerated recovery using magnesium ibogaine: characterizing the subjective experience of its rapid healing from neuropsychiatric disorders

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COClayton OlashDBDerrick Matthew BuchananRBRandi Brown

Key Points

  • This research aims to explore the subjective experiences of veterans undergoing magnesium-ibogaine treatment for neuropsychiatric disorders.
  • Analyzed narratives from 30 male veterans after a single magnesium-ibogaine treatment.
  • Used an open-label study design to collect qualitative data.
  • Employed a constructivist grounded-theory approach to identify experiential themes.
  • Identified four key experiential domains: trauma re-appraisal, altered self, emotional resolution, and embodied healing.
  • Participants reported vivid experiences of cognitive clarity and neural repair.
  • Findings suggest a self-directed psychotherapeutic process linked to rapid neuroplastic changes.

Abstract

Abstract Magnesium-ibogaine, a formulation combining ibogaine with pre- and post-treatment magnesium, was recently found to yield rapid clinical improvements in U.S. Special Operations veterans with TBI and PTSD. Yet, its therapeutic phenomenology during such healing is unknown. We analyzed post-session narratives from 30 male veterans who, after a single open-label magnesium-ibogaine treatment, answered three open-ended questions. A constructivist grounded-theory approach identified four recurrent experiential domains: dialogic trauma re-appraisal marked by guided replay of autobiographical memories; altered-self and mystical connectedness; emotional resolution with surges of forgiveness, love, and renewed purpose; and embodied healing, a vivid sense of neural repair accompanied by cognitive clarity and somatic relief. Together, these themes portray an accelerated, self-directed psychotherapeutic process that dovetails with previously reported improvements in this same cohort, suggesting mind–body mechanisms involving rapid neuroplastic change and highlighting its potential to inform novel approaches to trauma and TBI.

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Cite This Study

Olash et al. (2026) studied this question.

synapsesocial.com/papers/6980ffb4c1c9540dea81260dhttps://doi.org/10.1038/s44184-026-00185-7
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