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February 2, 20260 citationsOpen Access

Healthcare Costs and Mortality Trends of Elderly ICU Patients: Evidence from an Eight-Year Cohort Study in China

XZXiaohui ZhuMWMeiping WangYGYawei Guo

Key Result

Elderly ICU patients had the highest mortality, but their mortality decreased significantly from 19.5% in 2014 to 8.8% in 2021 (OR 0.86 per year, p<0.001) without a rise in real costs.

Key Points

  • To analyze healthcare costs and mortality trends among elderly ICU patients in China from 2014 to 2021.
  • Retrospective analysis of 31,535 ICU patients
  • 1:1:1 matching based on severity, comorbidities, sex, and admission type
  • Formation of three age groups: elderly (≥80 years), older (65-79 years), younger (16-64 years)
  • Comparison of costs and outcomes using appropriate statistical methods
  • Elderly patients represented 11.5% of ICU admissions
  • Elderly had the longest ICU stay (4.5 days) and highest mortality (11.5% ICU, 13.5% hospital)
  • Non-surgical elderly patients had lower costs, but surgery increased costs significantly by 124%
  • Drug costs declined while consumable costs rose from 32.0% to 42.0% of total costs
  • Mortality among elderly patients decreased significantly from 19.5% in 2014 to 8.8% in 2021

Study Design

Type

Cohort (n=31,535)

Structured PICO

P
Population
31,535 ICU patients admitted from 2014 to 2021, with 10,194 matched by severity, comorbidities, sex, and admission type into three age groups (≥80, 65-79, and 16-64 years).
O
Outcome
ICU mortality, hospital mortality, and inflation-adjusted healthcare costshard clinical

Elderly ICU mortality in China significantly declined from 2014 to 2021 without an increase in inflation-adjusted costs, though surgical interventions substantially increased expenses in this demographic.

Main Result

Odds Ratio: 0.86

Absolute Event Rate: 8.8% vs 19.5%

p-value: p=<0.001

Abstract

Background/Objectives: Elderly patients represent a growing proportion of ICU admissions, raising concerns about outcomes and healthcare costs. Evidence from China remains limited, yet understanding cost and mortality patterns is critical for optimizing care in aging populations. Methods: We retrospectively analyzed 31,535 ICU patients admitted from 2014 to 2021. After 1:1:1 matching on severity, comorbidities, sex, and admission type, three groups were formed: elderly (≥80 years), older (65–79 years), and younger (16–64 years), with 3398 patients each. Costs were inflation-adjusted, and outcomes compared across groups with appropriate statistical models. Results: Elderly patients accounted for 11.5% of admissions, had the longest ICU stay (4.5 vs. 3.8 vs. 3.1 days, p < 0.001), and the highest ICU (11.5%) and hospital (13.5%) mortality. Among non-surgical patients, elderly incurred the lowest costs; however, surgery reversed this pattern, producing a 124% increase. Expenditures were mainly driven by drugs and consumables. From 2014 to 2021, consumables rose from 32.0% to 42.0% of total costs, whereas drug costs declined. Inflation-adjusted hospital costs remained stable over time, while mortality among elderly patients decreased significantly (19.5% in 2014 vs. 8.8% in 2021; OR 0.86 per year, p < 0.001). Conclusions: Elderly ICU patients demonstrate unique cost and outcome profiles. While non-surgical elderly patients are less costly, surgery substantially increases expenses. Mortality declined over time without a rise in real costs, suggesting improved efficiency of critical care. These findings support tailored resource allocation and policy planning for aging ICU populations.

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Cite This Study

Zhu et al. (2026) conducted a cohort in ICU admission (n=31,535). Elderly age (≥80 years) vs. Older (65-79 years) and younger (16-64 years) age was evaluated on Mortality among elderly ICU patients (2021 vs 2014) (OR 0.86 per year, p=<0.001). Elderly ICU patients had the highest mortality, but their mortality decreased significantly from 19.5% in 2014 to 8.8% in 2021 (OR 0.86 per year, p<0.001) without a rise in real costs.

synapsesocial.com/papers/6980ffc6c1c9540dea81277ehttps://doi.org/10.3390/healthcare14030364
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