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February 5, 2026Scientific Reports0 citationsOpen Access

The investigation of initial endotracheal tube cuff pressures in the operating room: a multi-center cross-sectional study in China

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HPHeqi PengZTZhaohui TangYLYalin Li

Key Points

  • The study aims to investigate the management of endotracheal tube cuff pressures in Chinese operating rooms.
  • Multi-center cross-sectional study across 19 Grade A tertiary hospitals in China
  • Involvement of 2058 anesthetized patients
  • Measurement of initial cuff pressure within 30 minutes post-intubation
  • Assessment of methods used for cuff pressure estimation
  • Median initial cuff pressure was 48 cmH2O, with only 19% within the recommended range
  • Pilot balloon palpation was the most common method used (96.2%)
  • Direct manometry was the only method reliably achieving appropriate pressures
  • Independent risk factors for elevated cuff pressure included age < 60 years and trainee-performed inflation.

Abstract

Abstract Cuffed endotracheal tubes (ETTs) are widely used in general anesthesia, with recommended cuff pressure (CP) between 20 and 30 cmH 2 O in adults. This multi-center study investigated actual CP management practices across 19 Grade A tertiary hospitals in China, involving 2058 anesthetized patients. The median initial CP measured within 30 min post-intubation was 48 cmH 2 O (IQR 32–70), with only 19% within the recommended range (75.4% > 30 cmH 2 O; 5.6% 30 cmH 2 O) included: age < 60 years, pressure-controlled ventilation, absence of PEEP, ETT internal diameter < 7.0 mm, aminosteroid neuromuscular blocker use, and trainee-performed inflation. These findings highlight widespread challenges in optimal CP management across Chinese tertiary care centers.

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Cite This Study

Peng et al. (2026) studied this question.

synapsesocial.com/papers/69843371f1d9ada3c1fb093dhttps://doi.org/10.1038/s41598-026-37279-3
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