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February 5, 2026SHILAP Revista de lepidopterología1 citationsOpen Access

Evidence-based recommendations for the treatment of recurrent aphthous stomatitis: insights from an umbrella review

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NANader A. Al-AizariHAHashem Motahir Al-ShamiriBABayan K. AlShehri

Key Points

  • To evaluate treatments for recurrent aphthous stomatitis and provide evidence-based recommendations.
  • Conducted an umbrella review of existing studies on RAS treatments.
  • Analyzed the effectiveness of topical and systemic therapies for symptom control.
  • Focused on short-term treatment options and their applications.
  • Topical corticosteroids and hyaluronic acid are effective for short-term symptom relief.
  • Laser therapy shows potential in treating recurrent aphthous stomatitis.
  • Systemic agents should only be used for selected severe cases.

Abstract

Evidence supports topical corticosteroids, hyaluronic acid, and laser therapy for short-term symptom control in RAS, while systemic agents should be reserved for selected refractory cases.

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Cite This Study

Al-Aizari et al. (2026) studied this question.

synapsesocial.com/papers/698433d8f1d9ada3c1fb145ehttps://doi.org/10.1080/09546634.2026.2622245
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