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February 5, 2026Natural Product Reports1 citations

Isolation and synthesis of bisabosquals, fungal triprenyl phenol meroterpenoids with a densely functionalised bisabolane core

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JSJames P. ShephardDLDavid W. Lupton

Key Points

  • This research focuses on the isolation, biosynthesis, and bioactivities of bisabosquals and seco-bisabosquals.
  • Isolation of bisabosquals and seco-bisabosquals from fungal sources.
  • Analysis of bioactivities associated with these compounds.
  • Investigation of total synthesis methods for bisabosquals.
  • Successfully isolated bisabosquals and seco-bisabosquals from fungi.
  • Demonstrated bioactivities of the isolated compounds.
  • Developed methods for the total synthesis of these meroterpenoids.

Abstract

Bisabosquals and seco -bisabosquals are unusual fungal meroterpenoids with a densely functionalised bisabolane core. Herein, we highlight their isolation, biosynthesis and bioactivities along with studies on their total syntheses.

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Cite This Study

Shephard et al. (2026) studied this question.

synapsesocial.com/papers/6984343ff1d9ada3c1fb234ahttps://doi.org/10.1039/d5np00085h
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