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February 5, 2026Indian Journal of Ophthalmology - Case Reports0 citations

Sertraline induced bilateral acute angle closure glaucoma – An unusual report

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SMSanjitha Vilma MosesMRMeghana RavuriPGPai Shobha G

Key Points

  • To highlight the occurrence of bilateral acute angle closure glaucoma induced by sertraline in a patient with hyponatremia.
  • Case report of a 74-year-old female patient
  • Observation of symptoms following sertraline initiation
  • Management of intraocular pressure with antiglaucoma medications
  • Correction of hyponatremia and cessation of sertraline
  • Bilateral acute angle closure glaucoma developed 4 days after starting sertraline
  • Intraocular pressure was initially reduced with antiglaucoma medications
  • Complete control of glaucoma occurred only after stopping sertraline and correcting hyponatremia

Abstract

Bilateral acute angle closure glaucoma (AACG) is an uncommon ophthalmic emergency which can occur due to pupillary block or ciliochoroidal effusion. This can occur due to underlying risk factors which can be exacerbated with drugs in widespread use such as antidepressants – evidence with drugs such as Citalopram, Paroxetine being higher and substantially rarer in Sertraline. We report a case of a 74-year-old female who developed bilateral AACG 4 days after Sertraline initiation, who also had hyponatremia. Though antiglaucoma medications reduced the intraocular pressure, it was brought under control further only on cessation of the drug and hyponatremia correction. Unusual causes such as the above should not be overlooked, and multidisciplinary management is essential in preventing irreversible complications.

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Cite This Study

Moses et al. (2026) studied this question.

synapsesocial.com/papers/6984343ff1d9ada3c1fb23adhttps://doi.org/10.4103/ijo.ijo_1655_25
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