ABSTRACT Extravasation is a rare but serious complication of intravenous injections, particularly with irritant or vesicant drugs, which can lead to significant tissue damage. In this case report, we describe a 14‐year‐old boy who developed calcinosis cutis due to extravasation of calcium gluconate, resulting in extensive tissue necrosis. Although surgical debridement and grafting were performed, the patient subsequently experienced iatrogenic post‐surgical graft calcinosis cutis, leading to severe hand disability. This case underscores the importance of prompt recognition and management of extravasation to prevent long‐term complications.
Abtahi‐Naeini et al. (2026) studied this question.