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February 6, 2026Journal of NanobiotechnologyOpen Access

Super-resolution mapping reveals NAD⁺-delivering probiotic extracellular vesicles as nanotherapeutics for organelle protection and inflammation control

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Authors

GGGa-eun GoMKMinjae KangBHBo Kyoung Hwang

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Overview

Super-resolution mapping reveals NAD⁺ as a mechanism for infection-driven inflammation control via probiotics.

Key Points

  • The research aims to demonstrate the role of NAD⁺ in organelle protection and its effect on inflammation reduction mediated by probiotic EVs.
  • Utilized super-resolution mapping to analyze probiotics' effects on organelles.
  • Investigated the linkage between organelle integrity and inflammatory responses.
  • Assessed L. plantarum EVs as therapeutic candidates for inflammation.
  • Establishment of NAD⁺-mediated organelle protection as a central mechanism.
  • Demonstrated that probiotic EVs significantly reduce bacterial inflammation.
  • Highlighted L. plantarum EVs as potential nanotherapeutics for inflammation control.

Cite This Study

Go et al. (2026) studied this question.

synapsesocial.com/papers/698584f98f7c464f230083bchttps://doi.org/10.1186/s12951-026-04090-1
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