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February 6, 2026Annals of NeurologyOpen Access

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

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Authors

LILaura IbanezCPCyril PottierABAleksandra Beric

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Overview

This review explores the molecular mechanisms behind neurodegenerative diseases in the elderly, suggesting future research pathways.

Key Points

  • The aim is to synthesize knowledge on neurodegenerative diseases through genomic, transcriptomic, and proteomic insights.
  • Review of existing studies on Alzheimer's, Parkinson's, Lewy body dementia, and frontotemporal dementia.
  • Analysis of genetic, transcriptomic, and proteomic contributions to neurodegeneration.
  • Identification of novel biomarkers and disease mechanisms involved in neurodegenerative diseases.
  • Evidence supports multifactorial processes leading to neurodegenerative diseases.
  • Novel genes and proteins associated with neurodegeneration have been identified.
  • Biomarkers for early detection of neurodegenerative diseases have been highlighted.

Cite This Study

Ibanez et al. (2026) studied this question.

synapsesocial.com/papers/6985852f8f7c464f23008698https://doi.org/10.1002/ana.78170
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Current perspectives on the genetics of neurodegenerative diseases: A narrative review2026
  2. 2White Paper on Neurodegenerative Disease and Related Disorders and Associated Case Study2024
  3. 3Neurodegenerative Diseases: Mechanism, Limitations, and Emerging Treatments2025
  4. 4Influence of nutrition and epigenetics on the development of neurodegenerative diseases in elderly and old people2025 · 7 citations
  5. 5Advances in neurotherapeutics for neurodegeneration2026