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February 6, 2026European Heart Journal0 citations

Pacemaker risk calculator in patients candidates for transcatheter aortic valve implantation

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ITI Torres-ChilleronGEG Galeote EscaleraGSG Rivera Saltos

Key Result

A pre-TAVI risk calculator incorporating QRS width and the ratio between LVOT diameter and prosthesis diameter predicted post-TAVI pacemaker implantation with 68.4% sensitivity and 73.6% specificity.

Key Points

  • To develop a risk calculator that estimates the likelihood of pacemaker implantation before transcatheter aortic valve implantation (TAVI).
  • Ambispective cohort study design at a single center
  • Data collected from patients undergoing TAVI from January 2021 to December 2023
  • Exclusion of patients with previous pacemaker implantation
  • Use of descriptive statistics and logistic regression for analysis
  • 130 patients included, with 24 requiring pacemaker implantation post-TAVI (18.5%)
  • Identified independent predictors for pacemaker need: QRS width (p = 0.004) and LVOT/prosthesis diameter ratio (p = 0.035)
  • Calculator sensitivity of 68.4% and specificity of 73.6%

Study Design

Type

Cohort (n=130)

Multicenter

No

Structured PICO

Can a pre-TAVI risk calculator predict the need for pacemaker implantation in patients undergoing TAVI?

P
Population
130 patients undergoing transcatheter aortic valve implantation (TAVI) without a previous pacemaker.
I
Intervention
Pre-TAVI risk calculator incorporating QRS width and the ratio between left ventricular outflow tract diameter and prosthesis diameter.
O
Outcome
Pacemaker implantation post-TAVI.hard clinical

A pre-TAVI risk calculator using QRS width and LVOT-to-prosthesis diameter ratio can help predict the need for permanent pacemaker implantation after TAVI.

Abstract

Abstract Introduction and Objectives The development of cardiac conduction disorders (CCD) after transcatheter aortic valve implantation (TAVI) increases the incidence of pacemaker (PM) implantation. The objective of our study is to develop a risk calculator to estimate the probability of PM implantation in patients prior to the TAVI procedure, so our calculator will include only pre-TAVI predictors. Methods A single-center, ambispective cohort study including patients undergoing TAVI at our center between January 2021 and December 2023. Clinical-demographic data and pre-TAVI imaging parameters will be collected. Patients with a previous PM before TAVI will be excluded. The analysis will include descriptive statistics and logistic regression models. Results We included 130 patients, of which 24 required PM implantation post-TAVI (18.5%). Baseline characteristics of the sample are summarized in the table Table 1. QRS width and the ratio between the left ventricular outflow tract diameter and the prosthesis diameter were identified as independent predictors for PM implantation after TAVI (p = 0.004 and p = 0.035, respectively). Our calculator Figure 1 has a sensitivity of 68.4% and a specificity of 73.6%. Conclusions Our calculator establishes a predictive model that estimates the risk of PM implantation after TAVI. This provides a useful, accessible, and quick tool in clinical cardiology to predict one of the main complications for our patients.

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Cite This Study

Torres-Chilleron et al. (2025) conducted a cohort in Candidates for transcatheter aortic valve implantation (TAVI) (n=130). Pre-TAVI risk calculator was evaluated on Pacemaker implantation post-TAVI. A pre-TAVI risk calculator incorporating QRS width and the ratio between LVOT diameter and prosthesis diameter predicted post-TAVI pacemaker implantation with 68.4% sensitivity and 73.6% specificity.

synapsesocial.com/papers/698585db8f7c464f230099d7https://doi.org/10.1093/eurheartj/ehaf784.877
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