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February 6, 2026Journal of Personalized Medicine0 citationsOpen Access

Vitamin D Deficiency, Obesity, and Metabolic Parameters in Chilean Older Adults

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MÁMirelly ÁlamosBLBárbara LeytonAPAlejandra Parada

Key Points

  • This research aims to explore how vitamin D levels relate to obesity and metabolic health in older adults in Chile.
  • Conducted a cross-sectional analysis using data from the National Health Survey (2016-2017)
  • Included 1252 individuals aged 65 years and older
  • Used logistic regression models to assess associations between vitamin D levels, obesity, and metabolic health
  • Classified vitamin D levels into categories of sufficiency and deficiency
  • 88.3% of participants had suboptimal 25(OH)D levels (≤ 30 ng/mL)
  • 58.3% were classified as vitamin D deficient
  • Obesity was identified as an independent risk factor for vitamin D deficiency
  • Geographic location, female sex, and smoking status influenced deficiency risk significantly
  • No significant associations with type 2 diabetes or hypertension were found

Abstract

Background/Objectives: Vitamin D deficiency and obesity are prevalent public health concerns among older adults, with potential impacts on metabolic health. Despite high deficiency rates reported globally, data on their relationship in Chilean older populations remain limited. This study investigates the relationship between 25(OH)D status, obesity, and metabolic parameters in Chilean older adults using data from the 2016–2017 National Health Survey (ENS). Methods: A cross-sectional analysis was conducted in 1252 individuals aged ≥ 65 years with complete 25(OH)D and anthropometric measurements. Plasma levels of 25(OH)D were classified as optimal ≥ 30 ng/mL, insufficiency 20–29.9 ng/mL, deficiency 12–19.9 ng/mL, and severe deficiency < 12 ng/mL. Logistic regression models adjusted for age, sex, education, comorbidities, and environmental factors were used to assess associations. Results: The results demonstrated that 88.3% of older adults had 25(OH)D ≤ 30 ng/mL, with 58.3% presenting deficiency. Obesity was an independent risk factor for vitamin D deficiency across all models. Geographic location, female sex, and smoking also influenced deficiency risk, while no significant associations emerged with type 2 diabetes or hypertension. Conclusions: These findings highlight the need for targeted strategies addressing vitamin D insufficiency in older adults, considering regional and lifestyle factors, to improve health outcomes in this vulnerable population.

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Cite This Study

Álamos et al. (2026) studied this question.

synapsesocial.com/papers/698586118f7c464f23009ef1https://doi.org/10.3390/jpm16020090
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