CHA-Initiated 3 + 2 + 1 Spiroannulation of Enaminone with Diazo Oxindole Leading to Concise and Divergent Synthesis of Oxindole Spirohydropyridines

Key Points

• The aim is to create a concise and divergent synthesis method for oxindole spirohydropyridine derivatives.
• Utilized spiroannulation reaction of enaminone with diazo oxindole
• Employed various enaminone compounds to yield diverse derivatives
• Characterized resulting compounds using standard analytical techniques
• Successfully synthesized several oxindole spirohydropyridine derivatives
• Achieved high yields and purity in the synthesized compounds
• Demonstrated the potential for further variations in compound structures

Abstract