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February 8, 2026International Dental Journal0 citationsOpen Access

Combined Effects of Zinc Compounds and Xylitol on the Enzymatic and Anticandidal Activities of Salivary Antimicrobials

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YPYu-Jin ParkYKYoon-Young KimJCJi-Youn Chang

Key Points

  • The aim is to evaluate the effects of zinc compounds in combination with xylitol on salivary antimicrobial activities, specifically against oral candidiasis.
  • Analyzed enzymatic and antifungal activities using salivary samples
  • Tested combinations of zinc compounds and xylitol
  • Focused on effects in geriatric populations
  • Combination enhanced the antifungal activity of salivary antimicrobials
  • Zinc compounds and xylitol showed synergistic effects against oral candidiasis
  • Potential for these compounds in topical antifungal treatment strategies

Abstract

The combination of zinc compounds and xylitol may represent a potential candidate for topical antifungal strategies for preventing or managing oral candidiasis, especially in geriatric populations.

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Cite This Study

Park et al. (2026) studied this question.

synapsesocial.com/papers/698827570fc35cd7a8845fb1https://doi.org/10.1016/j.identj.2026.109415
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