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February 8, 2026Journal of Clinical Medicine0 citationsOpen Access

Fiberfill©—A New Bone Substitute for Treatment of Chronic Osteomyelitis?

HSHendrik SchöllmannVWVeronika WeichertCNClaas Neidlein

Key Points

  • This study analyzes the effectiveness of Fiberfill© as a bone substitute for patients with chronic osteomyelitis.
  • Retrospective analysis of patients treated with Fiberfill© between October 2022 and July 2024.
  • Endpoints included infection control, bone healing, and weight bearing function.
  • Descriptive data analysis performed on clinical and radiographic outcomes.
  • 38 patients analyzed with a mean age of 55.6 years.
  • 89% (34 patients) showed no signs of re-infection.
  • 92% (35 patients) exhibited complete or partial bone healing.
  • 78% (29 patients) achieved full weight bearing status.

Abstract

Background/Objectives: Therapy of osteomyelitis first aims to control infection of the bone and surrounding tissue. Once that is achieved, surgeons are regularly faced with defects of the bone as a result of the infection. Reconstruction of the bone is necessary. In the past years, various bone substitutes were developed. Since 2022, we have used Fiberfill© as a new allogenic material. The aim of this study is to analyze the outcome of patients with chronic osteomyelitis who received bone reconstruction with Fiberfill©. Methods: Patients who suffered from chronic osteomyelitis and received Fiberfill© for bone reconstruction between October 2022 and July 2024 were retrospectively analyzed. Endpoints were infection control, bone healing and function in terms of weight bearing. Data was analyzed descriptively. Results: 38 patients with a mean age of 55.6 years ± 16.4 years standard deviation were analyzed and seen for clinical and radiographic control after surgery with a mean follow up of 60 weeks up to three years. Mean defect size was 2.4 cm. Thirty-four patients (89%) did not have any re-infection. Complications associated with Fiberfill© were not found in any patients. Healing of the bone (completely and partially) was found in 35 patients (92%). Twenty-nine patients (78%) walked fully weight bearing. Seven patients were active with partial weight bearing at time of last follow-up (19%). Conclusions: Fiberfill© can be regarded as a bone substitute for reconstruction of bone defects in therapy of osteomyelitis. We did not find clear disadvantages or a high number of complications after filling up bone defects with Fiberfill©.

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Cite This Study

Schöllmann et al. (2026) studied this question.

synapsesocial.com/papers/6988278b0fc35cd7a884655bhttps://doi.org/10.3390/jcm15031277
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