PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 8, 2026Antimicrobial Resistance and Infection Control0 citationsOpen Access

Antimicrobial locks for the prevention of central line associated bloodstream infections in pediatric patients: a systematic review and network meta-analysis

NLNathan L’EtoileYLYun LIEHEricka Hayes

Key Points

  • This review aims to assess the effectiveness of antimicrobial locks in preventing central line associated bloodstream infections (CLABSI) in pediatric patients.
  • Conducted a systematic review and network meta-analysis of existing studies on antimicrobial locks.
  • Focused on primary and secondary prevention of CLABSI in pediatric populations.
  • Evaluated differences in efficacy based on the type of antimicrobial lock used.
  • Found a need for well-designed studies to confirm the effectiveness of antimicrobial locks.
  • Indicated potential differences in impact based on lock type, requiring further investigation.

Abstract

This review highlights the need for well-designed studies to determine the clinical effectiveness of antimicrobial locks for primary and secondary CLABSI prevention in specific pediatric populations and to determine whether there is differential impact by lock type.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

L’Etoile et al. (2026) studied this question.

synapsesocial.com/papers/698827f00fc35cd7a8847001https://doi.org/10.1186/s13756-026-01704-z
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1JBI Manual for Evidence Synthesis2024 · 2,249 citations
  2. 2Pediatric Central Venous Access Device Lock Solutions: A Network Meta-analysis2024 · 11 citations
  3. 3Effects of prophylactic use of taurolidine-citrate lock on the number of catheter-related infections in children under 2 years of age undergoing surgery2019 · 14 citations
  4. 4Prolonged Use of Ethanol Lock Prophylaxis With Polyurethane Catheters in Children With Intestinal Failure: A Single‐Center Experience2020 · 8 citations
  5. 5Hidden morbidity of ethanol lock therapy2017 · 11 citations