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February 8, 2026Human Genetics and Genomics Advances0 citationsOpen Access

The rate of identical-by-descent segment sharing between close and distant relatives

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AWAmy L. Williams

Key Points

  • This study aims to characterize the sharing of identical-by-descent segments among relatives of varying degrees.
  • Simulated 100,000 pairs of relatives from first to eighth cousins.
  • Included once removed and half-cousins in the analysis.
  • Modeled crossover interference and sex-specific genetic maps.
  • 98.5% of third cousins share at least one IBD segment.
  • 32.7% of fifth cousins and 0.96% of eighth cousins share IBD segments.
  • Sharing rates are higher than traditional models that ignore complex crossover features.

Abstract

Genetic relatives share long stretches of DNA they co-inherited from a common ancestor in identical-by-descent (IBD) segments. Because children inherit half their parents' genomes, the expected amount of DNA relatives share drops by 12 for each generation that separates them, being 2-d for d-degree relatives. Even so, there is substantial variance in sharing rates, such that most distant relatives share zero IBD segments. We characterized IBD segment sharing between relatives by simulating 100,000 pairs for each of first through eighth cousins, including once removed and half-cousins, while modeling both crossover interference and sex-specific genetic maps. Our results show that 98.5% of third cousins share at least one IBD segment, while only 32.7% of fifth cousins and 0.96% of eighth cousins have such sharing. These sharing rates are slightly higher than those that arise from models that ignore the more elaborate crossover features and can be filtered by segment length. The resulting segment count distributions are available with an interactive segment length threshold at https://hapi-dna.org/ibd-sharing-rates/.

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Cite This Study

Amy L. Williams (2026) studied this question.

synapsesocial.com/papers/698828b90fc35cd7a884870bhttps://doi.org/10.1016/j.xhgg.2026.100576
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